SEDRIC Overview

• The System for Enteric Disease Response, Investigation, and Coordination
  • Web-based platform (in the cloud) developed by CDC and Palantir Technologies
  • Facilitates collaborative multistate outbreak investigations of enteric disease
• SEDRIC is a customized, off-the-shelf web-based software system with four major capabilities
  • Integrate multiple surveillance data sources in real time
  • Visualize outbreak data rapidly in one place
  • Provide a secure platform for partner collaboration
  • Manage a repository of historic surveillance and outbreak data

• SEDRIC facilitates secure electronic data-sharing among partners during outbreak investigations
• Partners currently using SEDRIC are epidemiologists, laboratorians, and regulators from
  • State and local health departments
  • CDC
  • FDA
  • USDA-FSIS, USDA-APHIS

• CDC partners have access to SEDRIC for free
• Data Visualizations
  • Manage and visualize clusters under investigation
  • Visualize trends in time and space
  • Visualize relationships
• Data Management
  • Secure data sharing across agencies in real-time
  • Data exploration
  • Integration of future data sources

SEDRIC ingests surveillance data from PulseNet, NARMS, NORS, OMS, EDMI, and Epi Info as well as investigation data from epidemiologists, environmental health, regulatory agencies from state, federal partners. SEDRIC then compiles this information for data exploration, secure sharing, and visualization.

• Highlights
  • Intuitive GUI design, easy to learn
  • No software to download, entirely web-based
  • Surveillance data available in almost real-time
  • Multiple surveillance sources available under a single platform (and more being added!)
  • Fast (and pretty!) graphics
  • Secure, real-time data sharing
• Limitations
  • Not an analytical platform
  • Uni-directional data flow

• https://sedric.cdc.gov
• https://www.cdc.gov/foodsafety/outbreaks/investigating-outbreaks/sedric.html
  • Information about SEDRIC
  • Library of Training Documents
  • Link to login

• As of March 12, 2020:
  • SEDRIC upgraded platforms, no longer needing access to Java
  • Added integrations from Epi Info for our National Hypothesis Generating Questionnaire
  • Bulk uploading epidemiological updates has returned
  • Cluster detection
  • Allele Code/PFGE Pattern Crosswalk
  • … and much, much more!

• Home Screen
  • Navigate to multiple search features or select a tool to use
• Explore Outbreaks
  • Searchable information for events, from outbreak codes to NORS outbreaks to Outbreak Management System entries
• Explore and Update Isolates
  • Line list views, searchable isolate information, dashboards, and mapping
• Object Explorer
  • All searchable data for filtering, viewing, sorting, and summary statistics
• NHGQ
  • Overall views of NHGQ data, along with analyzable charts for each outbreak
• Test Results (NARMS)
  • Provides antimicrobial susceptibility results for both phenotypic and genotypic testing
• NORS Outbreak
  • Provides read-only information on NORS reports and allows searching across the NORS dataset
• Tools
  • Cluster detection
  • Allele code/PFGE pattern crosswalk
  • Pathogen predictor
  • Text analysis
  • FoodNet Calculator

• Welcome screen where buttons for views and tools can be found
• Contact user support
• User documents available

• Look at lists and dashboards of information on events
• Search across outbreaks
• Important documents and questionnaires housed in a single location
• Link to NORS

• Look at line list views and dashboards of isolate information
• Answer standard and ad hoc questions
• Store important documents and questionnaires in a single location
• Link to NHGQ data
• Bulk upload of isolates, through a specialized tool

• Search for anything available in the system
• Filter, map, sort, dashboards

• Direct linkage to Epi Info Web Surveys, syncs every 2 hours
• Searchable forms, vehicles, grocery stores
• Easy view form attached to isolates

• Direct linkage to NARMS, syncs every 2 hours from both phenotypic and predicted genotypic testing
• Searchable resistance patterns and drugs
• Easy view form attached to isolates

• All finalized reports now available
• Searchable from object explorer
• Full report attached to corresponding outbreaks

• Enables users to set easy parameters to find clusters of isolates based on allele codes
• Provides exportable listing of isolates for line list generation

• Provides a quick comparison of PFGE patterns under an allele code
• Provides a quick comparison of allele codes under a PFGE pattern (or pattern combination)

• Enter percentage of patients with certain symptoms, get back predicted pathogens to help figure out what testing may need completed

• Copy and paste, or type, text to get bar charts of word counts
• Word clouds also available
• Can remove common words from the analysis

• Use the binomial calculation against the static 2006-2007 FoodNet Population Survey dataset to determine statistical significance of a hypothesized vehicle

• Increased speed and efficiency in cluster management and triage
  • Easy, ad-hoc queries at our fingertips
  • Search across surveillance sources
  • Meeting times more effectively utilized
  • Increased efficiency in creating summaries and visualizations for meetings, presentations, publications
• Empowering state and local epidemiologists, laboratorians, and food safety staff to easily mine and visualize their own surveillance data
• Collaboration!

• Incorporation of allele codes for all pathogens, new analysis widgets
• Integrating COVIS data
• Integrating Shigella NNDSS data for outbreak response
• Connection with NCBI Pathogen Detection Pipeline
• Additional cluster detection tools